Yes. However, until you change the camshaft, you will not effect the airflow appetite or demand of the engine. I even make cams which will give you both a power and gas mileage improvement over the factory cam. And they idle perfectly.(If that is what you want.) I'll also guarantee them.
Use a Spread Bore 4 barrel rather than a Square Bore.(Spread bore carburetors have smaller front barrels than the back barrels.) But some 4 bbl intake manifolds will not accommodate the pattern of a spread bore. The right spread bore 4 barrel will get better gas mileage than your 2 barrel. A spread bore will also have better manners and better light throttle power than a square bore 4 barrel will. One inch thick '4 hole' carburetor spacers are your friend at low-mid rpm's on the street, too. Just make sure it's a spread or square bore spacer like your new carburetor is.