If you are running 150 shot wet the fueling off the jug might not be too terrible but the timing advance curve certainly will be. That size shot is going to require specialized tuning choices. Nitrous isn't for the street, seriously. Too fiddly for that.
What typically happens with a nitrous tune is the target lambda is locked so the computer doesn't pull fuel away from the injectors to meet the n/a target afr, due to the nitrous kit spraying in extra fuel. The timing curve is also usually locked so the ecm can't just add timing because at that second there's no knock. Both of these make for some pretty ****ty running habits off the jug.
2014 Premium GT, SGM, Brembo, Auto, Tech, Comfort, etc. GT500s, Steeda UCA, VMP auto N/A tune. 100 shot nitrous on BBR tune. Best e/t 11.42 at 120.64
2012 Premium GT, Candy Red, Brembo package, 3.73, MT82, Comfort, Tech, et al. Procal tune, Roush UCA, UMI poly LCA, GT500s, Steeda red bracket, Hoosier 28x10x16 bias drags. Best e/t 11.91 at 115.23 RIP