[RGR]

it is safe. just try to keep out of boost for 13hrs.

also, whenever you stop for a break, or when you get there or whatever, let it idle for about 2min (like you would a turbo). this will let the oil cool in the compressor

This means that as long as you are cruising at constant speeds,
(not 120 but maybe under 85 or so) that it will not make "boost"
and fuel consumption will be good too. Just set the CC and go!

 

[RGR]

now that his Q is answered, i'll hijack the thread and ask, what about a roots blower that'll be in boost at all times?

The supercoupe cars have a bypass that bleeds off boost @ cruise,
allowing better mileage and less wear and tear on the blower. Many
aftermarket systems have this too, it is a good item!